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Search Results for " b 70 "

Targets

10

Compounds

3

Natural Products

26

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T21652 RN-1 dihydrochloride Histone Demethylase , MAO
RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).
TQ0257 FICZ 6-Formylindolo[3,2-b]carbazole Aryl Hydrocarbon Receptor
FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).
T2059 Purvalanol A NG-60 Apoptosis , CDK , Autophagy
Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.
T6277 Doramapimod BIRB 796 Raf , p38 MAPK , Autophagy
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
T124637 1-O-(3,4,5-Trimethoxybenzoyl)-b-D-glucopyranoside
1-O-(3,4,5-Trimethoxybenzoyl)-b-D-glucopyranoside is a useful organic compound for research related to life sciences. The catalog number is T124637 and the CAS number is 56982-70-8.
T62212 Antitrypanosomal agent 4
Antitrypanosomal agent 4 (compound 19) is a potent antitrypanosomal agent that crosses the blood-brain barrier and shows good resistance to Trypanosoma cruzi and T. b. brucei with IC50 values of 1.2 μM and 70 nM respecti...
T79568 NPD-2975 Parasite
NPD-2975 (compound 30) is an orally active antitrypanosomal agent effective against Human African Trypanosomiasis (HAT), demonstrating acceptable metabolic stability and low toxicity potential in human MRC-5 lung fibrobl...
T36681 Sorafenib N-oxide
Sorafenib N-oxide is an active metabolite of sorafenib , an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases. Sorafenib N-oxide inhibits FLT3 that contains the internal tandem duplication mutation (FLT3-ITD; Kd =...
T37540 Amycolatopsin B
Amycolatopsin B is a bacterial metabolite originally isolated fromAmycolatopsisthat has anticancer activity.1It is cytotoxic to NCI H460 lung and SW620 colon cancer cells (IC50s = 0.28 and 0.14 μM, respectively). 1.Khali...
T36490 AZT triphosphate TEA
AZT triphosphate TFA (3'-Azido-3'-deoxythymidine-5'-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT tr...
Cat No. Product Name Synonyms Targets
TN5237 Virosine B Others
Virosine B is a natural product for research related to life sciences. The catalog number is TN5237 and the CAS number is 1052228-70-2.
TN4230 Huzhangoside B Others
Huzhangoside B is a natural product of Anemone, Ranunculaceae. The catalog number is TN4230 and the CAS number is 94795-70-7. Huzhangoside B can be used as a reference standard.
T37690 Phenylpyropene A
Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM)....

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01180 CD86 Protein, Human, Recombinant (His) Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-05157 TGFBR2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-06880 CD86 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-05390 CD86 Protein, Human, Recombinant (hFc) Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-05246 CD86 Protein, Human, Recombinant (His), Biotinylated Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-03082 TGFBR2 Protein, Rat, Recombinant (hFc) Rat HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-03171 TGFBR2 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPK-00880 B7-2 Protein, Human, Recombinant (His & Avi) Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00881 B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00653 B7-2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00882 B7-2 Protein, Human, Recombinant (hFc) Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPY-05133 CD86 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-01206 CD86 Protein, Mouse, Recombinant (His) Mouse HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-05386 CD86 Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPJ-00555 B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T...
TMPJ-00556 B7-2 Protein, Human, Recombinant (His) Human Human Cells
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T...
TMPY-05508 TGFBR2 Protein, Human, Recombinant (hFc) Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPJ-00873 CCL3L1 Protein, Human, Recombinant (His) Human Human Cells
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including che...
TMPY-05810 TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPK-00654 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His) Cynomolgus HEK293
IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the recept...
TMPK-00331 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated Human HEK293
IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the recept...
TMPK-00330 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi) Human HEK293
IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the recept...
TMPJ-01096 SLP-76 Protein, Human, Recombinant (His) Human E. coli
Lymphocyte cytosolic protein 2(LCP2)contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cel...
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi) Mouse HEK293
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of...
TMPK-01416 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we...
TMPK-01412 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) Human HEK293
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we...
CD86 Protein, Human, Recombinant (His)
TMPY-01180
Species: Human
Expression System: HEK293
TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
Species: Human
Expression System: Baculovirus-Insect Cells
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06880
Species: Human
Expression System: HEK293
CD86 Protein, Human, Recombinant (hFc)
TMPY-05390
Species: Human
Expression System: HEK293
CD86 Protein, Human, Recombinant (His), Biotinylated
TMPY-05246
Species: Human
Expression System: HEK293
TGFBR2 Protein, Rat, Recombinant (hFc)
TMPY-03082
Species: Rat
Expression System: HEK293
TGFBR2 Protein, Rhesus, Recombinant (hFc)
TMPY-03171
Species: Rhesus
Expression System: HEK293
B7-2 Protein, Human, Recombinant (His & Avi)
TMPK-00880
Species: Human
Expression System: HEK293
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00881
Species: Human
Expression System: HEK293
B7-2 Protein, Cynomolgus, Recombinant (His)
TMPK-00653
Species: Cynomolgus
Expression System: HEK293
B7-2 Protein, Human, Recombinant (hFc)
TMPK-00882
Species: Human
Expression System: HEK293
CD86 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05133
Species: Mouse
Expression System: HEK293
CD86 Protein, Mouse, Recombinant (His)
TMPY-01206
Species: Mouse
Expression System: HEK293
CD86 Protein, Mouse, Recombinant (hFc)
TMPY-05386
Species: Mouse
Expression System: HEK293
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00555
Species: Human
Expression System: Human Cells
B7-2 Protein, Human, Recombinant (His)
TMPJ-00556
Species: Human
Expression System: Human Cells
TGFBR2 Protein, Human, Recombinant (hFc)
TMPY-05508
Species: Human
Expression System: HEK293
CCL3L1 Protein, Human, Recombinant (His)
TMPJ-00873
Species: Human
Expression System: Human Cells
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05810
Species: Human
Expression System: HEK293
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His)
TMPK-00654
Species: Cynomolgus
Expression System: HEK293
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated
TMPK-00331
Species: Human
Expression System: HEK293
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi)
TMPK-00330
Species: Human
Expression System: HEK293
SLP-76 Protein, Human, Recombinant (His)
TMPJ-01096
Species: Human
Expression System: E. coli
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
TMPK-01413
Species: Mouse
Expression System: HEK293
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01416
Species: Human
Expression System: HEK293
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
TMPK-01412
Species: Human
Expression System: HEK293
Cat No. Product Name
L9830 Anti-Parkinson's Disease Compound Library

857 compounds
A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.
TargetMol